Trying to get Hybrid running an an M1 Mac

[Selur]

Doesn't matter where you place it. (In future AppImages I might place it inside the Hybrid.app/Contents/MacOS folder.)
The call says pip to install all the listed components.
If you open your terminal in the folder where the plugins.txt lies

python3 -m pip install -U -r plugins.txt

is fine otherwise you need to use

python3 -m pip install -U -r "PATH TOP plugins.txt"

(which can be tricky on macOS sometimes)

Cu Selur