Try a IVTC filter from Avisynth/Vapoursynth if those do not help, you probably won't get to a good result without a lot of tweaking.
might be a good start. No it's not supported in Hybrid since it simply has too many options which need to be adjusted to the source to be useful for most users:
Code:
AnimeIVTC (clip i, int "mode", int "aa", int "precision", int "killcomb", int "cache", bool "ifade", float "sfthr"*, bool "sfshow"* , bool "chrfix" , bool "blend" , bool "normconv" , int "pattern" , int "pass", bool "rendering" , int "bbob", int "cbob", string "edimode", int "degrain", int "omode" , int "cthresh"* , int "blockx"* , int "blocky"* , int "MI"* , int "tfmm"* , int "pp"* , int "metric"* , int "micmatching"* , int "i1", int "i2", int "e1", int "e2", int "e3", int "p1", int "p2" , bool "dchr"* , bool "palf"* , bool "tcfv1"* , bool "nvfr"* , bool "real30p"* , bool "autoAssuf"* , int "ediandnn"* , bool "o3025cfr"* , int "overlap", int "pel", int "search", bool "nnedi3pel"** , string "credconv" , bool "mode22"* , clip "ediext"* , string "bob4p"* , clip "extbob"* , string "extbobf"* , bool "repwithtdeint"* , float "dark", int "thin", int "sharp", int "smooth", bool "stabilize", int "tradius", int "aapel", int "aaov", int "aablk", string "aatype")