If Hybrid doesn't start after an update or if it doesn't recognize AviSynth when it should, you could try to delete the locally installed files (~/.hybrid-bin/ and ~/.hybrid/misc.ini) and let the starter script re-download everything.
I removed and re-installed, its showing a download dialog box then it doesn't open. I seem to be having trouble opening other applications as well(ubuntu software center) but firefox and deluge work. Should I switch to gnome rather than xfce as there are other errors as well
I wiped everything did a fresh install and added unity. Then installed hybrid(this time without avisynth). It doesn't open after the no gpu detected message